CONVERGENT APPROACHES TO THE VITAMIN-D SKELETON USING A TRANSITION-METAL CATALYZED CARBOMETALATION CAPTURE STRATEGY

Authors
NUSS JM MURPHY MM RENNELS RA HERAVI MH MOHR BJ
Citation
Jm. Nuss et al., CONVERGENT APPROACHES TO THE VITAMIN-D SKELETON USING A TRANSITION-METAL CATALYZED CARBOMETALATION CAPTURE STRATEGY, Tetrahedron letters, 34(19), 1993, pp. 3079-3082
Citations number
36
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
34
Issue
19
Year of publication
1993
Pages
3079 - 3082
Database
ISI
SICI code
0040-4039(1993)34:19<3079:CATTVS>2.0.ZU;2-0
Abstract
Two concise, highly convergent strategies for the synthesis of Vitamin D derivatives are presented. Beginning with synthons of exceedingly l ow complexity, each approach utilizes a transition metal catalyzed int ramolecular carbometalation for the stereoselective formation of the c ritical (bis)exocyclic diene subunit.