ENANTIOSELECTIVE PREPARATION OF POLYFUNCTIONAL SECONDARY ALLYLIC ALCOHOLS USING FUNCTIONALIZED DIALKYLZINCS PREPARED BY A COPPER(I) CATALYZED IODINE-ZINC EXCHANGE-REACTION

Authors
ROZEMA MJ EISENBERG C LUTJENS H OSTWALD R BELYK K KNOCHEL P
Citation
Mj. Rozema et al., ENANTIOSELECTIVE PREPARATION OF POLYFUNCTIONAL SECONDARY ALLYLIC ALCOHOLS USING FUNCTIONALIZED DIALKYLZINCS PREPARED BY A COPPER(I) CATALYZED IODINE-ZINC EXCHANGE-REACTION, Tetrahedron letters, 34(19), 1993, pp. 3115-3118
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
34
Issue
19
Year of publication
1993
Pages
3115 - 3118
Database
ISI
SICI code
0040-4039(1993)34:19<3115:EPOPSA>2.0.ZU;2-B
Abstract
Catalytic amounts of Cu(I) salts considerably facilitate the iodine-zi nc exchange reaction leading to polyfunctional dialkylzincs. The catal ytic asymmetric addition of these zinc reagents to a wide range of alp ha,beta-unsaturated aldehydes provides polyfunctional allylic alcohols with a high enantioselectivity.