R. Mayer et al., 2-DIMENSIONAL FILM DOSIMETRY APPLICATION IN HETEROGENEOUS MATERIALS EXPOSED TO MEGAVOLTAGE PHOTON BEAMS, Medical physics, 24(3), 1997, pp. 455-460
Measurement of dose within tissues and tissue interfaces having sharp
density discontinuities and heterogeneities (such as in the lung, esop
hagus, and rectum) is essential for treatment plan verification and ac
curate prediction of the prescribed dose. This study examines the feas
ibility and utility of simplifying standard film dosimetry to measure
dose distributions deposited by megavoltage beams in tissue substitute
s (such as cork for lung) and anthropomorphic phantoms which closely r
esemble human tissues having large density heterogeneities and having
sharp tissue interfaces. In addition, film dosimetry determined the do
se distribution involving superposition of multiple radiation fields a
nd helped evaluate the accuracy of a commercial treatment planning pro
gram which incorporates tissue heterogeneity effects through the ''eff
ective path length'' algorithm. This study shows that these treatment
planning programs and simple calculations overestimate the dose delive
red within the lower density material in heterogeneous regions. (C) 19
97 American Association of Physicists in Medicine.