ONE-POT PREPARATION OF 3-METHYLENEPYRROLIDINES WITH HIGH DIASTEREOMERIC EXCESS

Authors
VANDERHEIDE TAJ VANDERBAAN JL DEKIMPE V BICKELHAUPT F KLUMPP GW
Citation
Taj. Vanderheide et al., ONE-POT PREPARATION OF 3-METHYLENEPYRROLIDINES WITH HIGH DIASTEREOMERIC EXCESS, Tetrahedron letters, 34(20), 1993, pp. 3309-3310
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
34
Issue
20
Year of publication
1993
Pages
3309 - 3310
Database
ISI
SICI code
0040-4039(1993)34:20<3309:OPO3WH>2.0.ZU;2-S
Abstract
Addition of allylzinc reagents 1 to imines carrying a carbalkoxy group at C-alpha or C-alpha', followed by Pd(0)-catalyzed cyclization permi ts the one-pot preparation of 3-methylenepyrrolidines with high diaste reoselectivity.