PULMONARY-FUNCTION IN ADOLESCENTS WITH CHILDHOOD ASTHMA

The aim of this study was to determine the pulmonary function in forme r and present asthmatics. We examined 77 persons aged 12-24 years, cla ssified into four groups: 1) healthy subjects (controls) (n = 19), 2) former asthmatics (n = 19), 3) present mild asthmatics (n = 20), and 4 ) present severe asthmatics (n = 19). Although exhibiting no respirato ry symptoms, former asthmatics had reduced airflow values measured by FEV1 (median (range) 89.7 (83-99) vs 101.4 (91-110)) and MEF25 (76.5 ( 68-94) vs 103.0 (97-124)), as compared with controls. Furthermore, for mer asthmatics had significantly increased PEF variability, as compare d with controls, whereas no significant differences were found in stat ic lung parameters, i.e. total lung capacity and residual volume, as c ompared with controls. In conclusion, former asthmatics, although now exhibiting no respiratory symptoms, were found to have obstructive air flow limitation, increased bronchial responsiveness, and normal lung v olumes.