Vf. Trastek et al., DIAPHRAGMATIC-HERNIA AND ASSOCIATED ANEMIA - RESPONSE TO SURGICAL-TREATMENT, Journal of thoracic and cardiovascular surgery, 112(5), 1996, pp. 1340-1344
From 1985 to 1993, 49 patients (35 women and 11 men) with diaphragmati
c hernia and associated anemia underwent surgical repair. The median a
ge was 64.5 years (range 24 to 84 gears), Hematologic and gastroentero
logic evaluations revealed no other potential cause of bleeding. Each
patient had a diaphragmatic hernia, The median time between the diagno
sis of anemia and surgical repair mas 36 months (range 1 to 334 months
), Forty-five patients (91.8%) had received replacement therapy, inclu
ding iron for 33 and blood transfusions for 32 (median 6 units; range
2 to 70 units), Forty-six patients (93.9%) had symptoms: heartburn in
28, early satiety with bloating in 19, regurgitation in 11, dysphagia
in 7, and aspiration in 4, Preoperative upper gastrointestinal endosco
pic evaluation demonstrated gastric erosions at the level of the hiatu
s in 22 patients (44.9%), esophagitis in 7, stenosis in I, and Barrett
's disease in 1. An uncut CoIlis-Nissen fundoplication was performed i
n 44 patients, Belsey fundoplication in 2, a cut Collis-Nissen fundopl
ication, Nissen fundoplication, and Hill repair in I each, There was o
ne operative death (2% mortality), Complications occurred in 18 patien
ts (36.7%), Follow-up was complete and ranged from 4 to 103 months (me
dian 63 months), Forty-five patients (91.8%) had resolution of their a
nemia, Functional results, were excellent in 40 patients (81.6%), good
in 2 (4.1%), fair in 4 (8.2%), and poor in 3 (6.1%). In most patients
with diaphragmatic hernia and associated anemia refractory to medical
treatment, surgical repair can result in successful resolution of the
anemia.