CHEMICAL-STRUCTURE OF THE CORE REGION OF CAMPYLOBACTER-JEJUNI SEROTYPE O-2 LIPOPOLYSACCHARIDE

Authors
ASPINALL GO MCDONALD AG RAJU TS PANG H KURJANCZYK LA PENNER JL MORAN AP
Citation
Go. Aspinall et al., CHEMICAL-STRUCTURE OF THE CORE REGION OF CAMPYLOBACTER-JEJUNI SEROTYPE O-2 LIPOPOLYSACCHARIDE, European journal of biochemistry, 213(3), 1993, pp. 1029-1037
Citations number
27
Categorie Soggetti
Biology
Journal title
European journal of biochemistry → ACNP
ISSN journal
00142956
Volume
213
Issue
3
Year of publication
1993
Pages
1029 - 1037
Database
ISI
SICI code
0014-2956(1993)213:3<1029:COTCRO>2.0.ZU;2-8
Abstract
The complete structure for the core region of Campylobacter jejuni ser otype O:2 lipopolysaccharide (LPS) was assigned through studies on der ivatives of the liberated oligosaccharide (OS 2) and the intact LPS. S tructure determinations were performed using H-1-NMR spectroscopy, met hylation studies supported by fast-atom-bombardment mass spectrometry and linkage analysis by gas chromatography/mass spectrometry, Smith de gradation, and oxidation with chromium trioxide. It was concluded that complete oligosaccharide chains had the following structure: [GRAPHIC S]