SYNTHESIS OF THIAZOLO[4,3-A]ISOINDOLES BY INTRAMOLECULAR CYCLOADDITION-ELIMINATION REACTIONS OF -(SUBSTITUTED)IMINO-DELTA-2-1,2,3,4-THIATRIZOLINES

Authors
LABBE G LEURS S SANNEN I DEHAEN W
Citation
G. Labbe et al., SYNTHESIS OF THIAZOLO[4,3-A]ISOINDOLES BY INTRAMOLECULAR CYCLOADDITION-ELIMINATION REACTIONS OF -(SUBSTITUTED)IMINO-DELTA-2-1,2,3,4-THIATRIZOLINES, Tetrahedron, 49(20), 1993, pp. 4439-4446
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
49
Issue
20
Year of publication
1993
Pages
4439 - 4446
Database
ISI
SICI code
0040-4020(1993)49:20<4439:SOTBIC>2.0.ZU;2-I
Abstract
Fused thiazolidine 11 and thiazoline derivatives 19a-c are obtained by intramolecular cycloaddition-elimination reactions of appropriately s ubstituted 5-iminothiatriazolines 10 and 18a-c. The incorporation of a sidechain phenyl group excercises a favorable effect on cyclization s ince no reaction is observed with 25. Comparable intermolecular reacti ons also fail to occur.