All aspects of stroke management are best considered within the World
Health Organisation's framework of illness, which acknowledges four le
vels: pathology; impairment; disability, and handicap. Prevention ulti
mately aims to prevent death and minimise handicap. It may be targette
d at pathology, preventing cerebral infarction; impairment, preventing
symptoms and signs; disability, minimising dependence, or handicap, m
aximising freedom within society. The risk of recurrence of symptomati
c stroke is relatively low (10%/year) and the reduction in risk achiev
able is only modest (20% reduction). Consequently, it is always necess
ary to balance the risks of intervention, and the costs (e.g. in terms
of reduced pleasure or increased anxiety) against the potential benef
it. In severely dependent people, it is unlikely that intervention is
warranted.