An old dog had an expansile lesion affecting the ulnar diaphysis. The
lesion had clinical and radiographic features typical of a bone cyst;
however, computed X-ray tomography indicated that the lesion had a tis
sue content incompatible with a true cyst. The histological diagnosis
was osteosarcoma. This report emphasises the highly variable radiologi
cal appearance of canine osteosarcoma; biopsy is required to establish
the diagnosis because the radiological signs may mimic a lesion of di
fferent aetiology.