ASYMPTOMATIC CEREBRAL INVOLVEMENT IN SJOGRENS-SYNDROME - MRI FINDINGSOF 15 CASES

Fifteen patients with Sjogren's syndrome without clinical evidence of central nervous system disease were studied by MRI. Signal abnormaliti es were observed in 9 (60%). They were always visible on T2-weighted i mages as small punctate areas of high signal in the basal ganglia and the white matter of the cerebral hemispheres. Abnormalities were less frequently seen on T1-weighted images. Enlargement of cerebral sulci w as observed in 6 cases. The specificity and significance of these abno rmalities are discussed.