Practical approaches to optimization of the use of gadolinium in MR im
aging comprise a range of advances in data-acquisition techniques and
pulse sequences that augment tissue contrast and reduce scanning times
, increasing throughput and patient comfort. In addition to the effect
s of magnetic field strengths and manipulation of contrast doses for r
outine spin-echo (SE) imaging, several approaches are reviewed. These
include: fat suppression, which helps to resolve enhancing lesions fro
m tissues with inherently high signal on postgadolinium T1-weighted im
aging; gradient-echo (GRE) and partial radio-frequency (RF) echoplanar
techniques, which tend to reduce data acquisition times; MR angiograp
hy, which enables elucidation of slow-flow vessels and mass-vessel rel
ationships; and three-dimensional GRE scan displays, which relate lesi
on location to regional and surface anatomy.