R. Mullenbach et al., APPLICATION OF DNA FILTER HYBRIDIZATION AND PCR TO DISTINGUISH BETWEEN HUMAN AND NONHUMAN TISSUES OF POOR QUALITY, International journal of legal medicine, 105(6), 1993, pp. 307-309
The present report describes a novel approach for the identification o
f human or non-human specimens after long-term storage in a badly pres
erved state. The application of the PCR-technique (polymerase chain re
action) using human-specific primers as well as Southern blot (filter)
hybridization of the sample DNA to a primate-specific DNA probe enabl
ed us to extend the positive identification beyond the limits of conve
ntional methods such as serological or morphological examinations.