Gallium imaging offers many practical advantages over indium-111-label
ed leukocyte imaging, and calculating quantitative ratios in addition
to performing the routine bone-gallium images allows accurate and easy
evaluation of patients with suspected osteomyelitis. To add objectivi
ty and improve the accuracy and confidence in diagnosis of osteomyclit
is, quantitative comparison of abnormalities seen on bone scans and ga
llium scans was performed. One hundred and ten adult patients with 126
sites of suspected osteomyelitis were evaluated and categorized by ga
llium-to-bone ratios, gallium-to-background ratios, and spatial incong
ruency of gallium and bone activity. Combined evaluation using these c
riteria gave a 70% sensitivity and 93% specificity for the diagnosis o
f osteomyelitis.