Between July 1987 and May 1995, 11,315 patients underwent general thor
acic surgical procedures at our institution, In 47 of these patients (
0.42%), postoperative chylothorax developed, There were 32 men and 15
women with a median age of 65 years (range 21 to 88 years), Initial op
eration was for esophageal disease in 27 patients, pulmonary disease i
n 13, mediastinal mass in six, and thoracic aortic aneurysm in one, Al
l patients were initially treated with hyperalimentation, cessation of
oral intake, medium chain triglyceride diet, or a combination, Nonope
pative therapy was successful in 13 cases (27.7%), and oral intake was
resumed a median of 7 days later (range 2 to 15 days), Reoperation wa
s required in the remaining 34 cases, The reoperation rate varied acco
rding to the type of initial operation. Twenty-four of the 27 patients
(88.9%) who had undergone an esophageal operation required reoperatio
n, versus only five of 13 patients (38.5%) who had undergone pulmonary
resection (p < 0.001), Lymphangiography was performed in 16 patients
and identified the site of the leak in 13, The thoracic duct was ligat
ed in 32 of the 34 patients who required reoperation (94%), The remain
ing two patients were treated with mechanical pleurodesis and fibrin g
lue. Reoperation was successful in 31 of the 34 patients (91.2%), The
single death among the 47 patients (2.1%) occurred in the reoperated g
roup, Complications occurred in 18 patients (38.3%), Factors that pred
icted the need for reoperation were initial esophageal operation and a
verage daily postoperative drainage greater than 1000 ml/day for 7 day
s, We conclude that postoperative chylothorax is an infrequent complic
ation, Some cases can be managed without operation; however, we recomm
end early reoperation when drainage is greater than 1000 ml/day or if
the chylous fistula occurs after an esophageal operation, The fistula
can usually be controlled by ligation of the thoracic duct.