A. Casadevall et al., SUSCEPTIBILITIES OF SERIAL CRYPTOCOCCUS-NEOFORMANS ISOLATES FROM PATIENTS WITH RECURRENT CRYPTOCOCCAL MENINGITIS TO AMPHOTERICIN-B AND FLUCONAZOLE, Antimicrobial agents and chemotherapy, 37(6), 1993, pp. 1383-1386
Amphotericin B and fluconazole susceptibilities of 13 Cryptococcus neo
formans isolates from five patients with recurrent cryptococcal mening
itis were determined. For each patient, serial isolates showed no incr
ease in antibiotic resistance relative to the initial isolate. For the
se patients, recurrent disease was not due to drug resistance but may
reflect changes in immune function and/or poor compliance.