SUSCEPTIBILITIES OF SERIAL CRYPTOCOCCUS-NEOFORMANS ISOLATES FROM PATIENTS WITH RECURRENT CRYPTOCOCCAL MENINGITIS TO AMPHOTERICIN-B AND FLUCONAZOLE

Citation
A. Casadevall et al., SUSCEPTIBILITIES OF SERIAL CRYPTOCOCCUS-NEOFORMANS ISOLATES FROM PATIENTS WITH RECURRENT CRYPTOCOCCAL MENINGITIS TO AMPHOTERICIN-B AND FLUCONAZOLE, Antimicrobial agents and chemotherapy, 37(6), 1993, pp. 1383-1386
Citations number
26
Categorie Soggetti
Pharmacology & Pharmacy",Microbiology
ISSN journal
00664804
Volume
37
Issue
6
Year of publication
1993
Pages
1383 - 1386
Database
ISI
SICI code
0066-4804(1993)37:6<1383:SOSCIF>2.0.ZU;2-P
Abstract
Amphotericin B and fluconazole susceptibilities of 13 Cryptococcus neo formans isolates from five patients with recurrent cryptococcal mening itis were determined. For each patient, serial isolates showed no incr ease in antibiotic resistance relative to the initial isolate. For the se patients, recurrent disease was not due to drug resistance but may reflect changes in immune function and/or poor compliance.