INTRACYTOPLASMATIC SPERMATOZOA INJECTION WITH SURGICALLY OBTAINED SPERMATOZOA - NEW PATHS IN TREATMENT OF STERILITY

Intracytoplasmatic sperm injection (ICSI) of spermatozoa recovered by microsurgical epididymal sperm aspiration (MESA) or from a testicular biopsy specimen (TESE) can be successfully used for establishing pregn ancies. The high fertilisation rate of 60% (64 from 107 oocytes) and p regnancy rate (8 from 15 treatment cycles) endorses this treatment if congenital absence of vas deferens or obstructive azoospermia is suspe cted. Even in case of azoospermia resulting from complete induration o f the epididymis or tubular atrophy, spermatozoa could be recovered fr om the testis by open biopsy in four patients and one pregnancy result ed.