SYNTHESIS AND CONFIGURATIONAL ASSIGNMENT OF EPIMERIC 22-HYDROXY, 23, 24-ACETYLENIC, OLEFINIC OR EPOXY STEROIDS USING C-13 NMR-SPECTROSCOPY

Authors
HAZRA BG PORE VS JOSHI PL PADALKAR SN DESHPANDE SA RAJAMOHANAN PR
Citation
Bg. Hazra et al., SYNTHESIS AND CONFIGURATIONAL ASSIGNMENT OF EPIMERIC 22-HYDROXY, 23, 24-ACETYLENIC, OLEFINIC OR EPOXY STEROIDS USING C-13 NMR-SPECTROSCOPY, Magnetic resonance in chemistry, 31(6), 1993, pp. 605-608
Citations number
23
Categorie Soggetti
Spectroscopy,Chemistry
Journal title
Magnetic resonance in chemistry → ACNP
ISSN journal
07491581
Volume
31
Issue
6
Year of publication
1993
Pages
605 - 608
Database
ISI
SICI code
0749-1581(1993)31:6<605:SACAOE>2.0.ZU;2-0
Abstract
Stereoisomers of steroidal 22-hydroxy-, 23-acetylenic, 23-olefinic and 23, 24-isomeric epoxides were synthesized from C-22 aldehydes and the ir C-13 NMR spectra were analysed. A correlation regarding the combine d effect of the 22-hydroxy and 23, 24-substituents on the stereochemis try of the attached groups at C-22, -23 and -24 is derived.