STUDIES ON PLACENTAL-TRANSFER OF CELIPROLOL

Authors
KOFAHL B HENKE D HETTENBACH A MUTSCHLER E
Citation
B. Kofahl et al., STUDIES ON PLACENTAL-TRANSFER OF CELIPROLOL, European Journal of Clinical Pharmacology, 44(4), 1993, pp. 381-382
Citations number
2
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
European Journal of Clinical Pharmacology → ACNP
ISSN journal
00316970
Volume
44
Issue
4
Year of publication
1993
Pages
381 - 382
Database
ISI
SICI code
0031-6970(1993)44:4<381:SOPOC>2.0.ZU;2-B
Abstract
The maternofetal transfer of the beta1-selective adrenergic antagonist celiprolol has been studied in four hypertensive pregnant women. Feta l plasma concentrations were about 25-50 % of the levels found on the maternal side. There was no significant difference between the plasma concentrations of the two enantiomers in the child. Therefore, in furt her investigations only the racemate needs to be determined.