Se. Lapinsky et al., RAPID PULMONARY PHOSPHOLIPID ACCUMULATION INDUCED BY INTRAVENOUS AMIODARONE, Canadian journal of cardiology, 9(4), 1993, pp. 322-324
Amiodarone causes accumulation of phospholipids in lung alveolar cells
, and this phospholipidosis invariably is present when amiodarone pulm
onary toxicity is recognized. This effect has usually been demonstrate
d in patients following several months of therapy. The authors report
the occurrence of pulmonary phospholipidosis, diagnosed by bronchoalve
olar lavage, six days after commencing intravenous amiodarone therapy.