A validation study of the continuous noninvasive tonometric blood pres
sure monitor called JENTOW was performed in 20 normotensive subjects a
nd 10 hypertensive patients. Tonometric and intra-arterial blood press
ures were simultaneously recorded at supine rest and during a Valsalva
maneuver and tilting test. The results of the strict evaluation of th
e instrument's capacity for reproducing intra-arterial blood pressure
were as follows: 1) The overall frequency response of the transcutaneo
us blood pressure-monitoring system based on arterial tonometry was fl
at, with negligible delay to intra-arterial blood pressure in the rang
e of 0-5 Hz. 2) The largest discrepancy between intra-arterial and ton
ometric pressure waveforms was found at the early systolic phase; exce
pt for this phase, the tonometric waveform was almost equal to the int
ra-arterial waveform. 3) The beat-to-beat variability of tonometric pr
essure corresponded to that of intra-arterial pressure almost perfectl
y in the physiologically significant frequency range of 0-0.5 Hz. 4) D
uring resting conditions, the averages of the systolic and diastolic v
alues measured tonometrically corresponded well to those measured intr
a-arterially. 5) The changes in the between-method discrepancy of bloo
d pressure values during the Valsalva maneuver were statistically sign
ificant but small (<5 mm Hg). 6) No significant effect of postural til
ting was found on the between-method discrepancy. We conclude that thi
s method is clinically acceptable and reliable except for its limited
capacity for recording the higher frequency intra-arterial waveform an
d for responding to the relatively rapid and large transient changes i
n blood pressure.