The toxicity of cholecalciferol in the rabbit was evaluated as part of
an assessment of alternative toxins to sodium monofluoroacetate (1080
) and pindone for large-scale rabbit control in the South Island of Ne
w Zealand. After a dose-ranging study spanning the known LD50 values f
or other mammals (up to 400 mg kg - 1) an acute toxicity study establi
shed an LD50 of 9 mg kg - 1 and LD95 of 18 mg kg - 1 for the rabbit, w
hich proved very susceptible to cholecalciferol.