LAPAROSCOPIC SURGERY IS ASSOCIATED WITH LESS TUMOR-GROWTH STIMULATIONTHAN CONVENTIONAL SURGERY - AN EXPERIMENTAL-STUDY

Background The role of laparoscopic surgery for malignant disease is c ontroversial, To evaluate differences in tumour growth after conventio nal and laparoscopic surgery, an experimental study was performed in r ats. Methods After intraperitoneal injection of CC-531 colonic cancer cells or subcapsular renal implantation of CC-531 cancer cells, rats u nderwent either laparoscopically assisted small bowel resection, open small bowel resection or anaesthesia only. Peritoneal tumour growth an d subcapsular renal tumour growth were assessed after operation. Resul ts Peritoneal tumour growth was the least after anaesthesia only (P < 0.05) and less after laparoscopic than open resection (P < 0.05), Subc apsular renal tumour growth after either laparoscopic resection or ana esthesia only was less than after open resection (P < 0.01). Conclusio n Laparoscopic surgery was associated with less tumour growth than con ventional surgery in this experimental study.