CEREBROSPINAL-FLUID AND MRI FINDINGS IN 3 PATIENTS WITH MULTIPLE-SCLEROSIS AND SYSTEMIC LUPUS-ERYTHEMATOSUS

Three patients fulfilling the diagnostic criteria of both multiple scl erosis (MS) and systemic lupus erythematosus (SLE) were examined clini cally, immunologically and by magnetic resonance imaging (MRI). In all three patients MRI showed several high-signal lesions compatible with MS and, additionally, non-specific small white matter lesions suggest ing small vessel occlusion were seen. In CSF the cytoimmunological abn ormalities were variable and showed only slight to moderate immunoacti vation within the CNS at the time of sampling.