This 20-year retrospective review identifies 35 pediatric patients wit
h aural polyps in an attempt to assess for clinical predictors of sign
ificant otopathologic conditions. Chronic otitis media (43%), choleste
atoma (29%), and retained tympanostomy tubes (23%) were the common cau
ses. Unusual causes included mycobacterial infection and Langerhans' c
ell histiocytosis. Multivariate analysis revealed the co-occurrence of
conductive hearing loss at presentation to be a significant clinical
predictor (P=.03) of cholesteatoma; the histopathologic finding of ker
atin-induced giant cell reaction was nonspecific in this respect. Chol
esteatoma was also prevalent in recurrent polyp cases, suggesting the
need for prolonged follow-up in those children whose initial clinicopa
thologic evaluation does not yield a definitive diagnosis.