LOCALIZATION OF HEPATIC METASTASES BY RADIOLABELED ANTICARCINOEMBRYONIC ANTIGEN-ANTIBODY AND METAIODOBENZYLGUANIDINE IN A PATIENT WITH MEDULLARY-THYROID CARCINOMA

Sonography, computed tomography and magnetic resonance imaging examina tions did not detect recurrence or metastases of medullary thyroid car cinoma (MTC) in a patient with a rapidly rising serum calcitonin conce ntration after total thyroidectomy. Scintigraphy with technetium-99m l abelled anti-carcinoembryonic antigen antibody, Tc-99m-colloid and iod ine-131 metaiodobenzylguanidine indicated liver metastases. The three scintigrams were to some extent discrepant but from the combined infor mation the diagnosis of hepatic metastases could be established; it wa s subsequently verified by sonography and aspiration biopsy. This case demonstrates the usefulness of applying nuclear medicine imaging meth ods for the localization of hepatic MTC metastases.