PIPER METHYSTICUM - ENANTIOMERIC SEPARATION OF KAVAPYRONES BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

Authors
HABERLEIN H BOONEN G BECK MA
Citation
H. Haberlein et al., PIPER METHYSTICUM - ENANTIOMERIC SEPARATION OF KAVAPYRONES BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY, Planta medica, 63(1), 1997, pp. 63-65
Citations number
7
Categorie Soggetti
Pharmacology & Pharmacy","Plant Sciences","Chemistry Medicinal
Journal title
Planta medica → ACNP
ISSN journal
00320943
Volume
63
Issue
1
Year of publication
1997
Pages
63 - 65
Database
ISI
SICI code
0032-0943(1997)63:1<63:PM-ESO>2.0.ZU;2-S
Abstract
A simultaneous separation of the enantiomers of kawain, dihydrokawain, methysticin, and dihydromethysticin as well as the achiral dienolides yangonin and demethoxyyangonin was carried out on a ChiraSpher(R) NT column. This HPLC method can be used for the investigation of the enan tiomeric purity of plant material and herbal medicines. The influence of temperature and flow rate are discussed in respect to the chromatog raphic resolution of the enantiomers. All tested enolide racemates can be preparatively separated on ChiraSpher(R) NT.