A case of autoimmune oophoritis is reported. A 41 -year-old woman had
a total abdominal hysterectomy and bilateral salpingo-oophorectomy for
menorrhagia, polymenorrhoea and cystic ovaries. The diagnosis of auto
immune oophoritis was not suspected clinically, and was an unexpected
histological finding in the ovaries. The gross and histological appear
ances of this rare condition are described, and the lymphoid infiltrat
e characterised by immunocytochemistry. Recognition of this condition
by pathologists is important, as there is an associated risk of develo
ping other autoimmune disease, even some years later, necessitating cl
ose patient follow-up. In this case serum auto-antibodies to adrenal c
ortex were detected, indicating a subsequent risk of Addison's disease
.