PARTICIPATION OF COMPLEMENT IN NASAL POLYPOSIS

No changes in immunoglobulin (IgG, IgM and IgA) and complement compone nts C3 and C4 levels could be observed in patients suffering form both recurrent and acute nasal polyposis. However, in both groups of patie nts a significant decrease of the alternative pathway of complement ac tivation (up to 80 %) was found. In addition, patients suffering from the acute disease showed even decreased classical complement pathway ( up to 20 %). Examination of complement activation pathways was shown t o be advantageous for the follow-up of the course of this disease.