Ka. Kelley et al., INVITRO SUN PROTECTION FACTOR EVALUATION OF SUNSCREEN PRODUCTS, Journal of the Society of Cosmetic Chemists, 44(3), 1993, pp. 139-151
An in vitro method to evaluate sunscreen products for static sun prote
ction factor (SPF) was investigated. Surgical adhesive tapes were used
as substrates in a procedure modified from that originally described
by Diffey and Robson, 1989. The modified technique utilized a 150-watt
xenon arc solar simulator and an ultraviolet B radiometer. The in vit
ro SPF was calculated as the ratio of light transmission through untre
ated tape to that of sunscreen-treated tape and compared to SPFs deter
mined in vivo. Correlation between in vivo and in vitro SPF data varie
d tremendously. The sources of error were attributed to the structure
of the tape, absorption of the sunscreen active ingredients into the t
ape, and the detection limit of the radiometer used.