PREPARATION OF FRANCISELLA-TULARENSIS NONCAPSULAR VARIANTS

Authors
PAVLOVICH NV MISHANKIN BN DANILEVSKAYA GI KHODOVA VA RYZHKOVA VV TSIMBALISTOVA MI SUKHAR VV
Citation
Nv. Pavlovich et al., PREPARATION OF FRANCISELLA-TULARENSIS NONCAPSULAR VARIANTS, Zurnal mikrobiologii, epidemiologii i immunobiologii, (2), 1993, pp. 7-11
Citations number
9
Categorie Soggetti
Microbiology,Immunology,"Public, Environmental & Occupation Heath
Journal title
Zurnal mikrobiologii, epidemiologii i immunobiologii → ACNP
ISSN journal
03729311
Issue
2
Year of publication
1993
Pages
7 - 11
Database
ISI
SICI code
0372-9311(1993):2<7:POFNV>2.0.ZU;2-H
Abstract
New methods (selection in medium T with 20% Tween-80, inducing mutatio ns leading to the appearance of resistance to triphenyl tetrazolium ch loride or indoxyl phosphate) helped create a collection of F. tularens is stable noncapsular variants from strains of different subspecies. T he characteristic features of all F. tularensis cap- variants include inability to serologic tests with erythrocytic diagnosticums, the abse nce of capsular antigens, sensitivity to normal human serum.