SYNTHESIS OF LIPOPHILIC AND FLUORESCENT DERIVATIVES OF N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE

Citation
Ov. Bogomolov et al., SYNTHESIS OF LIPOPHILIC AND FLUORESCENT DERIVATIVES OF N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE, Bioorganiceskaa himia, 19(2), 1993, pp. 190-196
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
01323423
Volume
19
Issue
2
Year of publication
1993
Pages
190 - 196
Database
ISI
SICI code
0132-3423(1993)19:2<190:SOLAFD>2.0.ZU;2-Y
Abstract
Synthesis of lipophilic derivatives of N-acetylmuramyl-L-alanyl-D-isog lutamine (MDP) by condensation of the C-terminal amino acid moiety in MDP molecule with phosphatidylethanolamine was carried out. Fluorescen t lipophilic derivatives of MDP were synthesized by condensation of MD P with phosphatidylethanolamines labelled in the hydrophobic moiety, e . g. pyrenyl)stearoyl]-sn-glycero-3-phosphoethanolamine and pyrenylpho sphatidylethanolamine.