SYNTHESIS OF ACETAL PHOSPHOLIPIDS, 1,2-ALKYLIDENE-SN-GLYCERO-3-PHOSPHATES

Authors
KLYKOV VN OSTAPENKO OV SEREBRENNIKOVA GA
Citation
Vn. Klykov et al., SYNTHESIS OF ACETAL PHOSPHOLIPIDS, 1,2-ALKYLIDENE-SN-GLYCERO-3-PHOSPHATES, Bioorganiceskaa himia, 19(3), 1993, pp. 360-365
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Bioorganiceskaa himia → ACNP
ISSN journal
01323423
Volume
19
Issue
3
Year of publication
1993
Pages
360 - 365
Database
ISI
SICI code
0132-3423(1993)19:3<360:SOAP1>2.0.ZU;2-M
Abstract
A method for preparing natural acetal phospholipids (1,2-alkylidene-sn -glycero-3-phosphates) containing palmitic and oleic aldehyde residues was suggested. The method involves the condensation of the aldehydes with sn-glycero-3-phosphocholine and the enzymatic hydrolysis of the i ntermediate 1,2-alkylidene-sn-glycero-3-phosphocholines with phospholi pase D.