SYNTHESIS AND HPLC SEPARATION OF 6-FLUORO-L-DOPA METABOLITES

Citation
A. Luxen et al., SYNTHESIS AND HPLC SEPARATION OF 6-FLUORO-L-DOPA METABOLITES, Bulletin des Societes chimiques belges, 102(3), 1993, pp. 217-225
Citations number
16
Categorie Soggetti
Chemistry
ISSN journal
00379646
Volume
102
Issue
3
Year of publication
1993
Pages
217 - 225
Database
ISI
SICI code
0037-9646(1993)102:3<217:SAHSO6>2.0.ZU;2-0
Abstract
The synthesis of 6-fluoro-L-dopa metabolites (3-O-methyl-6-fluorodopa (1b), 6-fluorodopamine (2a), 3-O-methyl-6-fluorodopamine (2b), 3,4-dih ydroxy-6-fluorophenylacetic acid (3a) and 6-fluorohomovanillic acid (3 b)) is described. A HPLC method for their separation is also presented .