A. Hufnagel et al., SHORT-TERM-MEMORY - NO EVIDENCE OF EFFECT OF RAPID-REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION IN HEALTHY-INDIVIDUALS, Journal of neurology, 240(6), 1993, pp. 373-376
The effect of rapid-repetitive transcranial magnetic stimulation (rr-T
MS) on the immediate verbal and visuospatial memory span was assessed
by computerized neuropsychological testing in 11 healthy volunteers. T
he objective was to test whether rr-TMS may be utilized as a non-invas
ive tool for evaluation of memory function. The subjects had to memori
ze series of numbers (Digit-Span test) or the position of cubes (Corsi
-Block test) shown to them on a computer screen and actively reproduce
them immediately after the presentation. Synchronous with the appeara
nce of each item an rr-TMS train of 550 ms duration was delivered to t
he left or right anterolateral parietal as well as superior and poster
ior lateral temporal region at 50 Hz and with approximately 1.0 T stim
ulation intensity. Statistical comparison of memory performance during
rr-TMS and baseline testings without stimulation revealed no signific
ant changes. No adverse effects were observed. Thus, rr-TMS does not a
ffect short-term memory performance in healthy individuals under the s
timulation conditions described above.