Gehm. Dijkman et al., LONG-TERM FLUORIDE RELEASE OF VISIBLE LIGHT-ACTIVATED COMPOSITES INVITRO - A CORRELATION WITH INSITU DEMINERALIZATION DATA, Caries research, 27(2), 1993, pp. 117-123
Fluoridated composites are able to reduce or inhibit secondary caries
around fillings. The aims of this study were firstly to investigate th
e amount of F released in vitro from composites with a F content betwe
en 0 and 26 vol% as a function of time over a 1-year period. A second
aim was to correlate the in vitro data on F release with enamel demine
ralisation data in situ after a 1-month period. The results show that
all fluoridated composites release sizable amounts of F in solution, t
he total amounts of F released from three composites were proportional
to log t over at least 1 year. In one case proportionality of the tot
al amount of F released with t was observed. Possible mechanisms of F
release are considered. The results presented also show a linear relat
ion between the log of in vitro F release data and the effects on enam
el demineralisation in situ next to the composite. Extrapolation of th
e data reveals that a F release of about 200-300 mug/CM2 over a 1-mont
h period from a fluoridated composite would completely inhibit seconda
ry caries under plaque conditions.