Oocyte donation is now a 'routine' treatment for infertility. Oocyte d
onation is mainly carried out in women with primary ovarian failure or
premature menopause or in women in whom different regimens of ovarian
stimulation prevent the development of ovarian follicles. In our Cent
res, oocyte donation is also offered to women or couples who prefer no
t to use their own gametes because of high recurrent risk of chromosom
al or monogenic diseases. The resulting pregnancies in these women as
well as in a series of women with gonadal dysgenesis due to X-chromoso
me aneuploidies are reported,