ANTISPERM ANTIBODIES IN CRYPTORCHID BOYS

To explore whether the development of antisperm antibodies might play a role in inhibiting the future fertility of cryptorchid boys, 32 boys who underwent orchiopexy and 21 boys who underwent other inguinal sur geries were examined for the presence of antibodies to donor sperm. Th is group was compared to 23 boys who underwent noninguinal surgery or who had unrelated medical conditions. Using the indirect immunobead as say, 28% of the boys in the study group were found to have antisperm a ntibodies. These were predominantly of the IgG isotype. In the compari son group, only 1 boy (4%) had antisperm antibodies (P<0.05).