WERNERS-SYNDROME ASSOCIATED WITH SPASTIC PARAPARESIS AND PERIPHERAL NEUROPATHY

Authors
UMEHARA F ABE M NAKAGAWA M IZUMO S ARIMURA K MATSUMURO K OSAME M
Citation
F. Umehara et al., WERNERS-SYNDROME ASSOCIATED WITH SPASTIC PARAPARESIS AND PERIPHERAL NEUROPATHY, Neurology, 43(6), 1993, pp. 1252-1254
Citations number
9
Categorie Soggetti
Clinical Neurology
Journal title
Neurology → ACNP
ISSN journal
00283878
Volume
43
Issue
6
Year of publication
1993
Pages
1252 - 1254
Database
ISI
SICI code
0028-3878(1993)43:6<1252:WAWSPA>2.0.ZU;2-X
Abstract
A Werner's syndrome patient with spastic paraparesis and polyneuropath y had slowing of central and peripheral nerve conduction. Sural nerve biopsy revealed a significantly higher frequency of demyelination and remyelination and a loss of myelinated fibers. These data suggest that the central and peripheral nervous systems are affected in Werner's s yndrome.