In this study, the ventricle to brain ratios of catatonic subjects wer
e compared and evaluated with respect to the underlying diagnoses. Cat
atonic individuals with the diagnosis of schizophrenia were more likel
y to have greater ventricle to brain ratios than other catatonic subje
cts. The association of large ventricles with chronic, deteriorating p
sychosis is maintained and the heterogeneity of the syndrome of catato
nia is apparent. It is possible that the presence of large ventricles
may be useful to predict the chronicity of disability for some-cases o
f catatonia.