End-stage renal failure (ESRD) is more than a typical chronic disease.
Its treatment includes features which arguably make this condition un
ique. Selected psychosomatic aspects of ESRD are reviewed, including p
sychiatric morbidity, patients' adherence to their treatments, quality
of life and the emotional impact on staff involved in treating patien
ts with ESRD. Rather than presenting a comprehensive review of the res
ults of published research, particular emphasis is laid on the critica
l appraisal of the methodology of published studies, to examine the ex
tent to which these have provided answers to clinically important ques
tions.