Mj. Rumbak et al., CASE-REPORT - ACUTE POSTOPERATIVE RESPIRATORY-FAILURE CAUSED BY CHLAMYDIA-PNEUMONIAE AND DIAGNOSED BY BRONCHOALVEOLAR LAVAGE, The American journal of the medical sciences, 305(6), 1993, pp. 390-393
Most Chlamydia pneumoniae infections are mild, but 10% develop into pn
eumonia. C. pneumoniae has been observed in hospital in intubated pati
ents undergoing major surgery or admitted with severe trauma. A patien
t with squamous cell carcinoma in whom severe pneumonia developed post
pneumonectomy and who required mechanical ventilation is presented. Th
e patient was initially treated for nosocomial bacterial pneumonia wit
h the broad spectrum antibiotics ceftazidime, amikacin, and vancomycin
. The patient underwent a bronchoalveolar lavage, from which C. pneumo
niae was grown. Generally, these patients are a high-risk mortality gr
oup. Only after substituting the above antibiotics with doxycycline, t
o which C. pneumoniae was sensitive, did the pneumonia respond. Whethe
r this was a nosocomial or a community-acquired pneumonia is uncertain
.