TAKAYASUS DISEASE PRESENTING AS A NEPHROTIC SYNDROME DUE TO AMYLOIDOSIS

We report an 18 year old black woman who presented with nephrotic synd rome in whom the investigations led to the diagnosis of diffuse Takaya su's disease, renal amyloidosis of AA type and interstitial lung disea se. Proteinuria in Takayasu's disease is usually ascribed to hypertens ion or more rarely to glomerulonephritis. This case suggests that amyl oidosis should be considered also in the investigation of proteinuria in these patients in view of the serious prognostic implications. This case represents further evidence that Takayasu's disease can be the c ause of systemic reactive amyloidosis which may also be the presenting feature.