SERUM IGG ANTIBODIES TO HELICOBACTER-PYLORI IN PATIENTS WITH RECURRENT APHTHOUS STOMATITIS AND OTHER ORAL DISORDERS

Objectives. To compare the frequency of serum anti-Helicobacter pylori IgG antibodies in patients with recurrent aphthous stomatitis with pa tients with other oral ulcerative and nonulcerative disorders. Study d esign. Prospective study of serum IgG antibodies to H. pylori in 75 pa tients with recurrent aphthous ulcers, 15 patients with other oral ulc erative disorders, 41 patients with other oral mucosal lesions, 27 pat ients with oral dysaesthesia, and 25 healthy control patients without oral lesions. Results. The frequency of anti-H. pylori seropositivity was not significantly greater in patients with recurrent aphthous stom atitis (30.6%) compared with patients with other ulcerated oral mucosa l lesions (33.0%) and controls (24%). Conclusions. Helicobacter pylori does not appear to be of etiologic significance in the development of recurrent aphthous stomatitis.