Routing of cytosolically synthesized precursor proteins into chloropla
sts in a specific process which involves a multitude of soluble and me
mbrane components. In this review we will focus on early events of the
translocation pathway of nuclear coded plastidic precursor proteins a
nd compare import routes for polypeptides of the outer chloroplast env
elope to that of internal chloroplast compartments. A number of protei
ns housed in the chloroplast envelopes have been implied to be involve
d in the translocation process. but so far a certain function has not
been assigned to any of these proteins. The only exception could be an
envelope localized hsc 70 homologue which could retain the import com
petence of a precursor protein in transit into the organelle.