Ja. Ness et al., SENSORINEURAL HEARING-LOSS ASSOCIATED WITH AORTOCORONARY BYPASS-SURGERY - A PROSPECTIVE ANALYSIS, The Laryngoscope, 103(6), 1993, pp. 589-593
A prospective, clinical study was undertaken to assess the relationshi
p between aortocoronary by-pass surgery (ACBS) and sensorineural heari
ng loss (SNHL). Between August 1, 1988 and July 31,1989, 1458 patients
underwent ACBS and 181 volunteers were entered into the study based o
n availability and capability to complete preoperative and postoperati
ve questionnaires and audiometric testing. One hundred forty-five pati
ents completed the study. Intraoperative audiant brainstem response (A
BR) testing was performed on 7 patients with essentially normal hearin
g. Although 4 patients (2.8%) reported a subjective change in hearing
on postoperative questionnaires, objective testing did not confirm a s
ignificant hearing change in pure-tone, speech discrimination, or spee
ch reception threshold testing. Acute or sudden SNHL within 2 weeks fo
llowing ACBS was not identified in any patient completing the study. T
his study did not provide evidence to support a causal relationship be
tween SNHL and ACBS. However, if SNHL does occur following ACBS, the w
ell-established etiology of ototoxic therapy and subsequent SNHL deman
ds exclusion in the absence of conflicting histopathologic information
.