TESTICULAR ADRENAL-LIKE TISSUE IN A PATIENT WITH 17-ALPHA-HYDROXYLASEDEFICIENCY

Authors
GARCIAMAYOR RVG SOPENA B FLUITERS E PARAMO C MARTIN RF GALOFRE JC OLIVIE AA
Citation
Rvg. Garciamayor et al., TESTICULAR ADRENAL-LIKE TISSUE IN A PATIENT WITH 17-ALPHA-HYDROXYLASEDEFICIENCY, Hormone research, 38(5-6), 1992, pp. 241-244
Citations number
21
Categorie Soggetti
Endocrynology & Metabolism
Journal title
Hormone research → ACNP
ISSN journal
03010163
Volume
38
Issue
5-6
Year of publication
1992
Pages
241 - 244
Database
ISI
SICI code
0301-0163(1992)38:5-6<241:TATIAP>2.0.ZU;2-H
Abstract
Testicular adrenal-like tissue (TALT) have been observed in patients w ith congenital adrenal hyperplasia, and is usually associated with 21- hydroxylase deficiency; in 3 cases with 11beta-hydroxylase deficiency. We report a case of male pseudohermaphroditism with 17alpha-hydroxyla se deficiency (17OHD) who also had TALT. To our knowledge, this is the first report about the association of 17OHD and TALT. Also, the patie nt had high levels of serum aldosterone - an unusual finding in patien ts with 17OHD. A possible pathogenic mechanism is discussed.