REMARKABLY HIGH-RATE OF MOLECULAR EVOLUTION OF RUMINANT PLACENTAL LACTOGENS

Authors
Citation
M. Wallis, REMARKABLY HIGH-RATE OF MOLECULAR EVOLUTION OF RUMINANT PLACENTAL LACTOGENS, Journal of molecular evolution, 37(1), 1993, pp. 86-88
Citations number
23
Categorie Soggetti
Genetics & Heredity",Biology
ISSN journal
00222844
Volume
37
Issue
1
Year of publication
1993
Pages
86 - 88
Database
ISI
SICI code
0022-2844(1993)37:1<86:RHOMEO>2.0.ZU;2-U
Abstract
The sequences of ovine and bovine placental lactogens (based on publis hed cDNA sequences) are remarkably different, indicating a very rapid rate of evolution. Analysis of the cDNA sequences indicates that the r ate of nonsynonymous substitution in these proteins is considerably gr eater than the rate of synonymous substitution. This is an unusual sit uation, which suggests that the observed rapid rate of evolution is du e to incorporation of adaptive rather than neutral mutations.