J. Najda et al., THE ACTION OF EXCESSIVE, INORGANIC SILICON (SI) ON THE MINERAL METABOLISM OF CALCIUM (CA) AND MAGNESIUM (MG), Biological trace element research, 37(2-3), 1993, pp. 107-114
The influence of silicon treatment on the levels of calcium and magnes
ium in blood serum and tissues was studied in rats. The concentrations
of both elements were estimated in samples of sera and tissues of rat
s receiving per os a soluble, inorganic silicon compound-sodium metasi
licate nonahydrate (Na2SiO3 . 9H2O (REACHIM, USSR)), dissolved in the
animals' drinking water. A decrease of magnesium concentration in seru
m was observed with accompanying elevation of registered calcemia. Mor
eover, a reduction of tissue calcium levels was found with a simultane
ous increase of magnesium tissue pool. The results provide evidence fo
r silicon involvement in mineral metabolism. It could result in a modi
fication of pathological processes concerning bone tissue.