Zj. Zhu et al., SELENIUM CONCENTRATION AND GLUTATHIONE-PEROXIDASE ACTIVITY IN SELENIUM AND MAGNESIUM DEFICIENT RATS, Biological trace element research, 37(2-3), 1993, pp. 209-217
To clarify the effects of selenium (Se) and magnesium (Mg) deficiencie
s on Se and glutathione peroxidase (GSHPx) status, weanling male Wista
r rats weighing 50-60 g were placed on four kinds of diets divided by
two levels of Se (0.5 or 0.019 mg/kg) and Mg (500 or 50 mg/kg) for 8 w
k. Magnesium deficiency had an influence on distribution of Se, which
was increased in muscle and decreased in other tissues. The changes in
GSHPx matched those in Se. The levels of Se and GSHPx in most tissues
were lower in Se-Mg-deficient rats than in Se-deficient rats. Thus, s
elenium and Mg deficiencies would make oxidant lesion more serious tha
n Se deficiency.